Role Summary

We are seeking a highly motivated Senior Accountant to join our growing team. As Senior Accountant, you will be the primary preparer of most accounting workpapers and support, reporting to the Associate Director/Director of Accounting and SEC Reporting and working closely with the AP Manager. This is an exciting opportunity to contribute to the advancement of cutting-edge medical treatments and shape the future of healthcare.

We welcome applications from candidates located across the Northeast and Mid-Atlantic.

Primary Responsibilities

Participate in the monthly and annual accounting closing processes and contribute to producing accurate and timely financial statements
Prepare all recurring monthly journal entries
Maintain all balance sheet reconciliations and update monthly to ensure accurate reporting
Provide detailed fluctuation analysis for month end closing
Maintain effective internal controls and prepare annual internal control process narratives and key control analysis
Assist AP Manager in proper coding of invoices
Ensure financial records are maintained in compliance with GAAP
Support financial statement audits and reports
Collaboration with operational personnel on financial and operational matters
Special projects and other assignments as required

Required Skills And Qualifications

BA/BS degree in Accounting or related field
3-5 years of experience in an Accounting role
Ability to work effectively with all levels of an organization
Strong analytical skills with a high level of accuracy and attention to detail
Ability to manage competing priorities and deadlines and strong problem-solving skills
Strong written and verbal communication
Intermediate or Advanced aptitude in Excel is required
CPA or equivalent (or on-track) preferred
Experience with a Big 4 or national firm, SEC registered company and/or Biotech company is preferred
Familiarity with NetSuite and FloQast a plus
Ability to travel to HQ quarterly

About Lexeo
Lexeo Therapeutics is a clinical-stage genetic medicine company headquartered in New York City, pioneering cardiac genetic medicine candidates to treat the root causes of inherited cardiovascular diseases. Our lead program, LX2006, targets cardiomyopathy associated with Friedreich’s Ataxia and anchors a broader pipeline addressing genetically defined conditions such as hypertrophic and arrhythmogenic cardiomyopathies. Backed by a strong financial foundation, Lexeo is positioned to translate groundbreaking science into durable clinical impact.

Our work culture is a hybrid model with 2 days/week in the New York City office and 3 days working from home.

Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Lexeo Therapeutics

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